Humanization of antibodies targeting human herpesvirus 6B

A research group led by Professor Yasuko Mori (Division of Clinical Virology, Center for Infectious Diseases, Kobe University) has succeeded in humanization of mouse antibodies that can neutralize the infection caused by human herpesvirus 6B (HHV-6B). Infection by HHV-6B in infants can lead to complications such as encephalitis—brain inflammation—but an effective way to control the infection has not yet been found. Professor Mori's research team created "humanized" antibodies based on the mouse (murine) antibodies for HHV-6B. The findings were published on March 6 in the online edition of the Journal of Virology.
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